Clinical Trial

Mechanisms of Antipsychotic-Induced Insulin Resistance

Study Description

Molecular Mechanisms of Antipsychotic-induced Insulin Resistance

This study will investigate the molecular mechanisms of atypical-antipsychotic induced insulin resistance. This will be accomplished by administering olanzapine or placebo to healthy subjects for 7 days and analyzing genetic and protein changes in peripheral tissues known to play an important role in insulin resistance pathophysiology.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - olanzapine

atypical antipsychotic

Drug - placebo

placebo control

Additional Information

Official Study Title

Molecular Mechanisms of Antipsychotic-induced Insulin Resistance in Healthy Volunteers

Clinical Trial ID

NCT02708394

ParticipAid ID

0dN18b