Clinical Trial

Mental Health, Vascular Function, and Exercise Tolerance

Study Description

Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

Specific Aim #1: Examining the impact of mental health disorders (PTSD and GAD) on peripheral vascular function and sympathetic nervous system activity in young individuals. Specific Aim #2: Examining the impact of mental health disorders (PTSD and GAD) on peripheral hemodynamics and metabolic byproducts during small muscle mass exercise in young individuals. Specific Aim #3: Examining the impact of mental health disorders (PTSD and GAD) on exercise tolerance, peripheral hemodynamics and metabolic byproducts during large muscle mass exercise in young individuals.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Dietary Supplement - PTSD/GAD Antioxidant

Subjects will ingest an antioxidant cocktail containing 800 milligrams of alpha lipoic acid, 1 gram of vitamin C (ascorbic acid), and 400 milligrams of vitamin E (alpha tocopherol).

Dietary Supplement - PTSD/GAD Placebo

Subjects will ingest placebo (microcrystalline cellulose) pills.

Dietary Supplement - Healthy Control Antioxidant

Subjects will ingest an antioxidant cocktail containing 800 milligrams of alpha lipoic acid, 1 gram of vitamin C (ascorbic acid), and 400 milligrams of vitamin E (alpha tocopherol).

Dietary Supplement - Healthy Control Placebo

Subjects will ingest placebo (microcrystalline cellulose) pills.

Additional Information

Official Study Title

Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

Clinical Trial ID

NCT03216980

ParticipAid ID

0dNgze