Clinical Trial

Multi-Sensory Integration

Study Description

A Study of Human Multi-Sensory Integration

The primary aim of this study is to determine whether spatiotemporal characteristics of multisensory evoked potentials can be used as a marker of consciousness (awareness) under anesthesia. The secondary aim is to characterize changes in the characteristics of evoked potentials under anesthesia in both single sensory modality (visual, auditory) and across sensory modalities.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Propofol

Titration of propofol to minimal and moderate sedation as measured by Richmond Agitation-Sedation Scale with behavioral task performance over several hours.

Drug - Ketamine Injectable Product

Titration of ketamine to minimal and moderate sedation as measured by Richmond Agitation-Sedation Scale with behavioral task performance over several hours.

Additional Information

Official Study Title

A Study of Human Multi-Sensory Integration: A Neurophysiologic Correlate of Conscious Perception

Clinical Trial ID

NCT03498391

ParticipAid ID

6dBxoa