Clinical Trial

Dose Response of Epinephrine

Study Description

Dose Response of Epinephrine

Epinephrine is the principal physiologic defense against hypoglycemia in type 1 and longer duration type 2 DM. Despite this, it is unknown how epinephrine regulates in-vivo endothelial function and atherothrombotic balance in humans. The specific aim of our study will be to determine the dose response effects of the key ANS counterregulatory hormone epinephrine on endothelial function, fibrinolytic balance and pro-atherogenic inflammatory mechanisms in healthy humans.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Epinephrine

Dose response of epinephrine infusion

Saline infusion

Placebo

Additional Information

Official Study Title

Hypoglycemia Associated Autonomic Dysfunction Dose Response of Epinephrine

Clinical Trial ID

NCT02692313

ParticipAid ID

7axLPa