Clinical Trial

Assessment of Portal Hypertension with Multiparametric MRI

Study Description

Assessment of Portal Hypertension With Multiparametric MRI

The purpose of this study is to determine whether new multiparametric magnetic resonance imaging (MRI) methods (including diffusion-weighted MRI, dynamic contrast-enhanced MRI, MR elastography and phase-contrast imaging) can be useful in assessing liver damage and degree of portal hypertension (a complication of advanced liver fibrosis and cirrhosis) secondary to chronic liver disease, compared to ultrasound measurement of liver stiffness [acoustic radiation force impulse (ARFI) ultrasound] and routine blood tests. MRI uses magnetic fields to look at soft tissues in the body. This study will ultimately help to determine whether these methods will be useful in identifying liver disease and their complications that cannot be well-understood using current liver MRI techniques.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Procedure - mpMRI

Multiparametric MRI

Procedure - ARFI US

Acoustic radiation force impulse is a type of ultrasound elastography

Additional Information

Official Study Title

Assessment of Portal Hypertension With Multiparametric MRI

Clinical Trial ID

NCT03436550

ParticipAid ID

9avEMe