Clinical Trial

Probiotics to Promote Oral Health

Study Description

Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health

This study will examine the mechanisms of action of probiotics and synbiotics for control of oral diseases, with a particular focus on exploring new strategies for caries prevention and treatment.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Caries Free 1.5% Arginine

Study toothpaste assigned containing 1.5% Arginine. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

Caries Free Placebo Sodium Fluoride

Marketed Toothpaste containing 1100 ppm F as Sodium Fluoride will be assigned. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

Caries Active 1.5% Arginine

Study toothpaste assigned containing 1.5% Arginine. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

Caries Active- Placebo Sodium Fluoride

Marketed Toothpaste containing 1100 ppm F as Sodium Fluoride will be assigned. Subjects will also receive a Colgate Wave Comfort Adult Toothbrush to brush their teeth with twice a day.

Additional Information

Official Study Title

Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health

Clinical Trial ID

NCT02999230

ParticipAid ID

9avk0b