Clinical Trial

Treatment of High Blood Pressure

Study Description

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

The purpose of the study is to show the blood pressure lowering effect of aprocitentan, a new drug, when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure (hypertension), and to show that blood pressure reduction is kept for long period of time.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Drug - Aprocitentan 12.5 mg

Tablet, oral use

Drug - Aprocitentan 25 mg

Tablet, oral use

Drug - Placebo

Matching placebo tablet

Additional Information

Official Study Title

Multi-center, Blinded, Randomized, Parallel-group, Phase 3 Study With Aprocitentan in Subjects With Resistant Hypertension (RHT)

Clinical Trial ID

NCT03541174

ParticipAid ID

BeXjvb