Clinical Trial

Does Testosterone Effect Polycystic Ovary Syndrome

Study Description

Effect of High Testosterone on Sleep-associated Slowing of Follicular Luteinizing Hormone (LH) Frequency in Polycystic Ovary Syndrome

The purpose of this study is to determine whether a testosterone receptor blocker (flutamide) will normalize sleep-wake luteinizing hormone pulse frequency relationships in women with polycystic ovary syndrome.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Flutamide

Flutamide, 250 mg capsule for oral administration, twice a day for 4 weeks (or menstrual cycle length in normally-cycling controls)

Drug - Placebo

Placebo, for oral administration, twice a day for 4 weeks (or menstrual cycle length in normally-cycling controls)

Additional Information

Official Study Title

Influence of Hyperandrogenemia on the Sleep-associated Slowing of Follicular LH Frequency in Adult Polycystic Ovary Syndrome

Clinical Trial ID

NCT00930228

ParticipAid ID

Ddwjwb