Clinical Trial

Methods for Stabilization in Opioid Dependence

Study Description

Buprenorphine as Adjunct to Outpatient Induction Onto Vivitrol

The study will enroll 30 opioid-dependent participants into an open-label pilot outpatient study of methods to facilitate induction and stabilization onto XR-NTX. There will be three different methods of XR-NTX induction using increasing doses of oral naltrexone and buprenophine.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Buprenorphine

Buprenorphine will be administered daily

Drug - Naltrexone

On study day 2, participants will receive increasing doses of oral naltrexone prior to administration of XR-NTX

Drug - Vivitrol

Participants will receive one 380 i.m. injection on Study day 5 or 10, and another injection 4 weeks later.

Additional Information

Official Study Title

Buprenorphine as Adjunct to Outpatient Induction Onto Vivitrol

Clinical Trial ID

NCT03113409

ParticipAid ID

DdwqMa