Menopausal Sleep Fragmentation and Body Fat Gain
Study Description
“Menopausal Sleep Fragmentation and Body Fat Gain”
This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin response as a metabolic biomarker for body fat gain.
Location
Methods
Pharmaceutical medication involved
Patients and healthy individuals accepted
Drug - Leuprolide Acetate
one injection of open-label intramuscular dose of leuprolide (3.75-mg depot), a gonadotropin-releasing hormone agonist that rapidly suppresses estradiol and temporarily achieves ovarian suppression.
Fragmented sleep
Fragmented sleep will be experimentally induced.
Additional Information
Official Study Title
Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in Women
Clinical Trial ID
NCT03047330
ParticipAid ID
DdwvMb
