The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus
Study Description
“The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus”
Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.
Location
Methods
Pharmaceutical medication involved
Patients and healthy individuals accepted
Drug - Naloxone
Blinding/labeling/preparation of agents: No blinding is required in this study. The study drug will be prepared, unit dose labelled, and patient labelled according to institutional protocols. Storage: Secured at room temperature in the central pharmacy then dispensed as a patient specific supply and stored at room temperature the automated dispensing cabinet. No more than a 24 hour supply will be dispensed at any given time. Administration: 1 mg/ml oral solution administered enterally (oral, nas ...read more on ClinicalTrials.org
Additional Information
Official Study Title
The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus
Clinical Trial ID
NCT03176316
ParticipAid ID
NbWEJe
