Clinical Trial

The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus

Study Description

The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus

Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Naloxone

Blinding/labeling/preparation of agents: No blinding is required in this study. The study drug will be prepared, unit dose labelled, and patient labelled according to institutional protocols. Storage: Secured at room temperature in the central pharmacy then dispensed as a patient specific supply and stored at room temperature the automated dispensing cabinet. No more than a 24 hour supply will be dispensed at any given time. Administration: 1 mg/ml oral solution administered enterally (oral, nas ...read more on ClinicalTrials.org

Additional Information

Official Study Title

The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus

Clinical Trial ID

NCT03176316

ParticipAid ID

NbWEJe