Clinical Trial

Safety of Intranasal Irrigation Probiotics

Study Description

Safety of Intranasal Irrigation Probiotics in Healthy Volunteers

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases, affecting the quality of life of patients who suffer. Despite medical and surgical treatments available, there are a significant number of people suffering from CRS refractory to these standard treatments. A preliminary clinical trial conducted at CHUM HA?tel-Dieu, has allowed us to evaluate the therapeutic potential of intranasal irrigation of probiotics in patients with CRS. This treatment administered twice daily for 14 days was well tolerated and resulted in improved chronic rhinosinusitis symptoms. Prior to deployment on a larger scale, the safety of this therapy must be confirmed in a healthy population, free of sinus disease. Therefore, this study aims to assess the safety of the use of probiotic intranasal irrigation in healthy volunteers.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Probiotics

Safety of nasal irrigation with probiotics in healthy volunteers

Additional Information

Official Study Title

Safety of Intranasal Irrigation Probiotics in Healthy Volunteers

Clinical Trial ID

NCT02933918

ParticipAid ID

PdRrEd