Clinical Trial

Resistance Exercise and Muscle Synthesis

Study Description

Nutritional Strategies to Augment the Postprandial Muscle Protein Synthetic Response to the Ingestion of a Low Dose of Protein in Middle-aged Women

Using stable isotope methodology, investigators will determine the postabsorptive and postprandial muscle protein synthetic response in 60 female adults (Age 50-79, BMI: <30 kg/m2) immediately after an acute bout of resistance exercise. Participants will be divided in to 5 groups of twelve women (n=12). Each group will receive a different protein beverage or placebo to consume following the resistance exercise training. Group 1 will consume a beverage consisting of whey protein; group 2 will consume whey protein supplemented with additional leucine; group 3 will consume whey protein supplemented with additional leucine and hydrolyzed whey peptides; group 4 will consume whey protein supplemented with additional leucine and citrulline; group 5 will just consume water. During the testing, blood and muscle samples will be collected.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - Resistance Exercise

Participants will perform unilateral leg extension exercise immediately prior to ingestion of the experimental beverage

Dietary Supplement - 14 g Whey protein

Dietary Supplement - 6.6 g Whey protein + 1.25 g leucine

Dietary Supplement - 4 g Whey protein + 1.25 g leucine + 2.6 g Whey peptides

Dietary Supplement - 6.6 g Whey protein + 1.25 g leucine + 0.8 g Citrulline

Water control

Additional Information

Clinical Trial ID

NCT02918981

ParticipAid ID

PdyOna