Clinical Trial

Impact of Escitalopram on Sperm DNA Fragmentation

Study Description

Impact of Escitalopram on Sperm DNA Fragmentation

Double-blind placebo-controlled randomized trial of daily escitalopram for 6 weeks in healthy men with normal semen analyses and no psychiatric history of depression, bipolar, mania or suicidal ideation. Hormone profiles, semen analysis, sperm DNA fragmentation, and sexual function will be measured at baseline, after 6 weeks of therapy, and 4 weeks after discontinuation of therapy (10 weeks into study).

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Escitalopram

10mg by mouth daily for 6 weeks

Placebo

matched placebo control by mouth for 6 weeks

Additional Information

Official Study Title

Assessing the Impact of Escitalopram on Sperm DNA Fragmentation: A Randomized Placebo Controlled

Clinical Trial ID

NCT03527043

ParticipAid ID

QbY4Aa