“Impact of Escitalopram on Sperm DNA Fragmentation”
Double-blind placebo-controlled randomized trial of daily escitalopram for 6 weeks in healthy men with normal semen analyses and no psychiatric history of depression, bipolar, mania or suicidal ideation. Hormone profiles, semen analysis, sperm DNA fragmentation, and sexual function will be measured at baseline, after 6 weeks of therapy, and 4 weeks after discontinuation of therapy (10 weeks into study).
Drug - Escitalopram
10mg by mouth daily for 6 weeks
matched placebo control by mouth for 6 weeks
Assessing the Impact of Escitalopram on Sperm DNA Fragmentation: A Randomized Placebo Controlled