Clinical Trial

Glucagon-Like Peptide-2 Mediated Secretion of Enteral Lipids

Study Description

Glucagon-like Peptide-2 Mediated Secretion of Stored Enteral Lipids

Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) releases the triglyceride from the gut is not known. The research team in this study is interested in finding out how teduglutide (a degradation resistant form of GLP-2) releases stored triglyceride from the gut by studying samples from patients undergoing endoscopy and small bowel biopsy.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Drug - Teduglutide

Teduglutide

Drug - Placebo

Placebo

Additional Information

Official Study Title

Investigating the Release of Stored Enteral Lipids in Response to a Single Subcutaneous Dose of Analogue Glucagon-like Peptide-2 in Humans

Clinical Trial ID

NCT03442972

ParticipAid ID

QeZ28e