Clinical Trial

Stroke Motor Rehabilitation

Study Description

Premotor Cortex: A New Target for Stroke Motor Rehabilitation

The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Device - rTMS (Control 1)

Location of rTMS: premotor cortex Frequency of rTMS: 0.1 Hz Time of rTMS: 400 milliseconds after the onset of movement-related EMG Device: Super Rapid 2 Transcranial Magnetic Stimulator

Device - rTMS over Premotor Cortex (Contralateral Hemisphere)

Location of rTMS: premotor cortex Frequency of rTMS: 0.1 Hz Time of rTMS: 50 milliseconds before the onset of movement-related EMG Device: MagStim Super Rapid 2 Transcranial Magnetic Stimulator

Device - rTMS over Premotor Cortex (Ipsilateral Hemisphere)

Location of rTMS: premotor cortex Frequency of rTMS: 0.1 Hz Time of rTMS: 50 milliseconds before the onset of movement-related EMG Device: Super Rapid 2 Transcranial Magnetic Stimulator

Device - rTMS (Control 2)

Location of rTMS: somatosensory cortex Frequency of rTMS: 0.1 Hz Time of rTMS: 50 milliseconds before the onset of movement-related EMG Device: Super Rapid 2 Transcranial Magnetic Stimulator

Device - rTMS (Control 3)

Location of rTMS: premotor cortex Frequency of rTMS: 0.1 Hz Time of rTMS: 50 milliseconds before the onset of movement-related EMG Device: Super Rapid 2 Transcranial Magnetic Stimulator with Sham Coil

Motor Training

During motor training, participants will quickly extend their hand at a pace of one extension every 5 seconds (0.2Hz) in response to an auditory cue.

Additional Information

Official Study Title

Premotor Cortex: A New Target for Stroke Motor Rehabilitation Using Transcranial Magnetic Stimulation

Clinical Trial ID

NCT02565199

ParticipAid ID

RdGg3d