Clinical Trial

Circulating Tumor Cells in Patients with Rectal Cancer

Study Description

Circulating Tumor Cells in Patients With Rectal Cancer

Objectives: - To establish the rate of circulating tumor cells (CTC) positivity in patients with locally-advanced rectal cancer (LARC), relative to other stages; - To assess changes in detected CTCs associated with neoadjuvant therapy in patients with LARC; - To correlate CTC counts with neoadjuvant treatment response as an indicator of disease risk.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Procedure - Blood Draws

Healthy Participants: Blood (about 2 tablespoons) drawn at 1 time point. Rectal Cancer Participants: Blood (about 2 tablespoons) drawn 1 time before participant starts treatment. Blood also drawn: Just before tumor surgery 1-8 weeks after surgery, or before chemotherapy begins 1-12 weeks after last dose of chemotherapy year after surgery, OR 1 year after completion of treatment if no surgery years after surgery, OR 2 years after completion of treatment if no surgery If the disease gets worse dur ...read more on ClinicalTrials.org

Additional Information

Official Study Title

Circulating Tumor Cells in Patients With Rectal Cancer

Clinical Trial ID

NCT02874885

ParticipAid ID

RdGxJe