Clinical Trial

Predictors of Outcomes in Psychiatric Disorders

Study Description

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

In this study the investigators will seek to improve our understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of mood, substance use, and eating behavior. The investigators will recruit 1000 individuals and use a wide range of assessment tools, neuroimaging measures, blood and microbiome collections and behavioral tasks to complete the baseline and follow-up study visits. Upon completion, the investigators aim to have robust and reliable dimensional measures that quantify these systems and a set of assessments that should be recommended as a clinical tool to enhance outcome prediction for the clinician and assist in determining who will likely benefit from what type of intervention.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - standardized diagnostic assessment

Behavioral - self-report questionnaires

Behavioral - behavioral tasks

physiological measurements

structural and functional magnetic resonance imaging and EEG

biomarker and microbiome assessments

blood to derive induced pluripotent stem cells

genetic and epigenetic assessments

Additional Information

Official Study Title

T-1000: Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

Clinical Trial ID

NCT02450240

ParticipAid ID

Xe0XVe