Clinical Trial

Alcohol, Cannabis, and Driving Sub-Study I

Study Description

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Active inhaled delta-9-THC

Low dose THC (~4 mg), dissolved in alcohol. This dose is roughly equivalent to smoking approximately 1/4 of a marijuana cigarette, or "joint". Administered over 20 minutes via a vaporizer.

Drug - Placebo

Control: Approximately 4 drinks of orange juice or ginger ale covered by a trace amount of ethanol on the surface, each administered over approximately 10 minutes.

Drug - Placebo

Control: No active THC. Administered over 20 minutes via a vaporizer. approximately 10 minutes.

Drug - Active Oral Ethanol

0.4 g/kg ethanol in orange juice or ginger ale to reach a target BrAC of approximately 0.04%. This dose is equivalent to consuming approximately 2 standard drinks over 1 hour. Approximately 4 drinks, each administered over approximately 10 minutes.

Additional Information

Official Study Title

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

Clinical Trial ID

NCT02709954

ParticipAid ID

YaO9Ed