Clinical Trial

Cocaine Use Disorder and Cortical Dopamine

Study Description

Cocaine Use Disorder and Cortical Dopamine

The goal of this study is to use [C-11]FLB 457 and amphetamine (oral, 0.5 mg/kg) to measure cortical dopamine transmission in cocaine dependent individuals and healthy controls

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - d-amphetamine

oral d- amphetamine 0.5 mg/kg is used to stimulate dopamine release in the brain

Radiation - [C-11]FLB 457

PET radiotracer

Additional Information

Official Study Title

Imaging of Cortical Dopamine Transmission in Cocaine Dependence

Clinical Trial ID

NCT03349606

ParticipAid ID

YaOrGe