Clinical Trial

Mitochondrial Remodeling After Exercise

Study Description

Mitochondrial Remodeling After Exercise

Regulation of mitochondrial health in overweight and obese individuals may be impaired. The purpose of this study is to identify impairments in regulation of mitochondrial health within skeletal muscle and to determine if short-term exercise training (2-weeks) can reverse such impairments. The investigator's hypothesis is that pathways that serve to degrade poorly functioning mitochondria in overweight and obese individuals are down-regulated, but that short-term exercise training can restore these pathways to improve skeletal muscle mitochondrial function.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - Short-term Exercise Training

Participants will perform 2-weeks of supervised exercise training on a stationary bike.

Additional Information

Official Study Title

Mitochondrial Remodeling After Exercise

Clinical Trial ID

NCT04103424

ParticipAid ID

aQWMld