Clinical Trial

Physiological Flow of Liquids in Healthy Swallowing

Study Description

Physiological Flow of Liquids in Healthy Swallowing

Thickened liquids are commonly used as an intervention for people with dysphagia (swallowing impairment). However, the field currently lacks a proper understanding of how this intervention works. The overall goal of the project is to collect measurements of bolus flow through the oropharynx (i.e., mouth and throat) during swallowing. The factors that are expected to influence bolus flow include the liquid/food consistency (i.e., thin, slightly-thick, mildly-thick, moderately-thick, extremely thick, solid) and the forces applied during swallowing (i.e., tongue pressures and swallowing muscle contraction). The objective is to determine how these factors interact to influence the flow of a bolus through the oropharynx in healthy swallowing.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Starch-thickened liquids

Thickener added in amounts required to reach slightly thick, mildly thick, moderately thick and extremely thick consistencies, as defined by the International Dysphagia Diet Standardisation Initiative flow test.

Xanthan-gum thickened liquids

Thickener added in amounts required to reach slightly thick, mildly thick, moderately thick and extremely thick consistencies, as defined by the International Dysphagia Diet Standardisation Initiative flow test.

Combination Product - Barium concentration

Commercially available barium products diluted to different concentrations (i.e., 20% w/v, 40% w/v) through the addition of water

Food consistency

Commercially available food products in different consistencies: Carr's Table Water crackers, Squish gummy candies, baby carrots

Additional Information

Official Study Title

Physiological Flow of Liquids in Healthy Swallowing

Clinical Trial ID

NCT04114617

ParticipAid ID

av23ma