Clinical Trial

Fructose: Substrate, Stimulus, or Both?

Study Description

Fructose: Substrate, Stimulus, or Both?

This objective of this study is to use sensitive methodology under controlled conditions to investigate the mechanisms by which fructose consumption contributes to excess fatty acid synthesis and elevations in blood glucose levels following consumption of meals containing fructose.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

High fructose, fructose labeled meal

Liquid meal containing high fructose (16% of energy), labeled with 2-13C fructose

High fructose, pyruvate labeled meal

Liquid meal containing high fructose (16% of energy), labeled with 2-13C pyruvate

Low fructose, fructose labeled meal

Liquid meals containing low fructose (6% of energy), labeled with 2-13C fructose

Low fructose, pyruvate labeled meal

Liquid meal containing low fructose (6% of energy), labeled with 2-13C pyruvate

Additional Information

Official Study Title

Fructose: Substrate, Stimulus, or Both?

Clinical Trial ID

NCT04168372

ParticipAid ID

av2Gra