Clinical Trial

Investigation of the Gut Microbiome and Statin Response

Study Description

Investigation of the Gut Microbiome and Statin Response

There is evidence that the bacteria that naturally reside in the gut can influence how well we respond to medications. Therefore this study will look at how rosuvastatin, a medication used to lower cholesterol levels, may change the bacteria in the gut. Investigators will also examine how the gut bacteria will affect the ability of rosuvastatin to lower cholesterol levels. There will be 4 study visits over the course of about 16 weeks.The expected duration of the study is 2 years. Investigators plan to enroll 100 healthy volunteers during that time.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Rosuvastatin

rosuvastatin 20 mg daily or placebo for eight weeks

Drug - Placebo

Matched placebo control

Additional Information

Official Study Title

INvestigation of the Gut microbiomE and STatin Response (INGEST)

Clinical Trial ID

NCT04098003

ParticipAid ID

axkg9e