Clinical Trial

Acute Maternal Hyperoxygenation in CHD

Study Description

Acute Maternal Hyperoxygenation in CHD

Congenital heart disease (CHD) is predominantly detected before birth. Using echocardiography and MRI, this study will determine whether acute exposure to maternal hyperoxygenation (MH) leads to measurable increases in fetal cerebral oxygenation from baseline in fetuses with CHD. The study aims to determine whether MH could be used as a chronic in-utero treatment strategy to promote brain growth/maturation to birth and to improve postnatal neurodevelopmental outcomes, and identify the types of CHD most likely to benefit from chronic MH.


Locations Selected Location


No pharmaceutical medication involved No pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Oxygen gas

Transient maternal oxygen administration during echocardiographic and MRI imaging

Additional Information

Official Study Title

Congenital Heart Disease (CHD): Hemodynamic Effects of Acute Maternal Hyperoxygenation in the Fetus

Clinical Trial ID


ParticipAid ID