Clinical Trial

Adiposity and Endothelin Receptor Function

Study Description

Adiposity and Endothelin Receptor Function

Elevated levels of ET-1 have been implicated in cardiovascular disease and some forms of hypertension. Due to the strong, positive correlation between obesity and hypertension, the present study will explore the contribution of adiposity in ETB receptor function and aim to elucidate if ETB receptor dysfunction is a major contributor to hypertension in obesity.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Candesartan

7 days of Candesartan (16mg/day)

Drug - Placebo

7 days of Placebo

Additional Information

Official Study Title

Adiposity and Endothelin Receptor Function

Clinical Trial ID

NCT03583866

ParticipAid ID

b4xxxb