“Adiposity and Endothelin Receptor Function”
Elevated levels of ET-1 have been implicated in cardiovascular disease and some forms of hypertension. Due to the strong, positive correlation between obesity and hypertension, the present study will explore the contribution of adiposity in ETB receptor function and aim to elucidate if ETB receptor dysfunction is a major contributor to hypertension in obesity.
Drug - Candesartan
7 days of Candesartan (16mg/day)
Drug - Placebo
7 days of Placebo
Adiposity and Endothelin Receptor Function