Clinical Trial

Laparoscopic Assisted Plane Block (LAPB) Trial

Study Description

Laparoscopic Assisted Plane Block (LAPB) Trial

This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Bupivacaine

utilizing local anesthetic to perform a regional block under laparoscopic guidance

Drug - Exparel 266 milligram Per 20 ML Injection

utilizing local anesthetic to perform a regional block under laparoscopic guidance

Drug - Saline

placebo injection of saline

Additional Information

Official Study Title

Laparoscopic Assisted Plane Block (LAPB) Trial: Bupivacaine Versus Liposomal Bupivacaine Versus Standard Local Anesthesia for Post-operative Analgesia

Clinical Trial ID

NCT03730402

ParticipAid ID

b68m9e