“Blood Markers of Early Pancreas Cancer”
Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an individual's chance of surviving the disease. The investigators propose a longitudinal study of subjects at higher than average risk of PDAC in order to generate clinical data and bank serial blood specimens.
Diagnostic Test - Mixed Meal Tolerance Test
The goal of the test is to determine hormone secretion from the pancreas and small intestine in response to the mixed meal.
Diagnostic Test - Hemoglobin A1c
This test provides the average level of blood glucose over the last 3 months.
Diagnostic Test - Other exploratory blood biomarkers
Other exploratory blood biomarkers including cell free DNA and other markers in development
A Longitudinal Cohort Study to Identify Clinical and Blood Markers of Early Pancreas Cancer