Perioperative Lidocaine and Ketamine in Abdominal Surgery
Study Description
“Perioperative Lidocaine and Ketamine in Abdominal Surgery”
The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
Location
Methods
Pharmaceutical medication involved
Patients and healthy individuals accepted
Drug - Lidocaine and ketamine
Perioperative lidocaine and ketamine infusion (see below for dosages and timings)
Drug - Lidocaine
Perioperative lidocaine infusion (1.5 mg/kg bolus followed by an infusion of 2 mg/kg/hour based on actual body weight; the bolus and infusion will be started after anesthesia induction and before surgical incision, and continued until 1 hour after transfer from the operating room to the PACU)
Drug - Ketamine
Perioperative ketamine infusion (0.5 mg/kg bolus followed by an infusion of 0.3 mg/kg/hour based on actual body weight; the bolus and infusion will be started after anesthesia induction and before surgical incision, and continued until 1 hour after transfer from the operating room to the PACU)
Drug - Placebo
Perioperative placebo infusion (normal saline)
Additional Information
Official Study Title
Lidocaine and Ketamine in Abdominal Surgery
Clinical Trial ID
NCT04084548
ParticipAid ID
bW6Jva
