Clinical Trial

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

Study Description

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who regularly exercise are protected from these effects.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Dietary Supplement - High Sodium

10 days of 3900 mg of sodium/day in excess of normal dietary intake delivered via enteric capsules filled with table salt.

Placebo

10 days of enteric capsules filled with dextrose.

Additional Information

Official Study Title

The Role of Oxidative Stress and Endothelial Dysfunction in High Sodium-Induced Changes in Pulsatile Hemodynamics

Clinical Trial ID

NCT04233957

ParticipAid ID

bW6xXa