Testing Experimental Treatment for Frontotemporal Dementia

Eligibility Details: Inclusion Criteria: - At screening, female participants must be nonpregnant and nonlactating - In good physical health on the basis of no clinically significant findings from medical history, PEs, laboratory tests, ECGs, and vital signs. - Participant is a carrier of a loss of function GRN mutation or carrier of a hexanucleotide repeat expansion C9orf72 mutation Exclusion Criteria: - Known history of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric, human, or humanized antibodies or fusion proteins. - History of alcohol abuse or substance abuse - Participant resides in a skilled nursing facility, convalescent home, or long term care facility