Clinical Trial

Organ Congestion in Severe Acute Kidney Injury

Study Description

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

Fluid overload is associated with adverse outcomes in patients with severe acute kidney injury. It remains unclear if fluid overload is merely a marker of disease severity or if organ congestion is a mediator of complications. Point-of-care ultrasound could be a modality used to assess organ congestion and its clinical implications. The objective of this study is to determine whether ultrasound markers of organ congestion are associated with major adverse kidney events in critically ill patients with severe acute kidney injury.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Diagnostic Test - Portal vein flow

Doppler assessment performed on day 0, 3 and 7.

Diagnostic Test - Intra-renal flow

Doppler assessment performed on day 0, 3 and 7.

Diagnostic Test - Hepatic vein flow

Doppler assessment performed on day 0, 3 and 7.

Diagnostic Test - Pulmonary B-lines

Ultrasound assessment of performed on day 0, 3 and 7.

Diagnostic Test - Dimensions of the inferior vena cava

Ultrasound assessment of performed on day 0, 3 and 7.

Diagnostic Test - Left ventricular function

Ultrasound assessment of performed on day 0, 3 and 7.

Diagnostic Test - Right ventricular function

Ultrasound assessment of performed on day 0, 3 and 7.

Additional Information

Official Study Title

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

Clinical Trial ID

NCT04095143

ParticipAid ID

bkR15a