Pharmacokinetics of Oxytocin at Cesarean Delivery
Study Description
“Pharmacokinetics of Oxytocin at Cesarean Delivery”
The primary objective is to obtain data to inform the design of a population pharmacokinetic study of oxytocin after administration at CD as per standard institutional practice.
Location
Methods
Pharmaceutical medication involved
Patients and healthy individuals accepted
Drug - oxytocin
PK measurements of oxytocin
Device - Shore durometer
The investigators will take serial readings from a digital durometer at the uterine fundus at 3, 6, 9 and 12 minutes following OXT administration to provide data that will inform an estimate of the timing of peak effect. Shore durometers measure the hardness of materials on a scale of 0-100 Shore Units (SU). Preliminary (unpublished) data provided a range of 10-56 SU after oxytocin administration at cesarean delivery. Durometer readings were also shown to correlate positively with the obstetrici ...read more on ClinicalTrials.org
Additional Information
Official Study Title
The Pharmacokinetics of Oxytocin in Pregnant Women Undergoing Cesarean Delivery - a Feasibility Pilot Study
Clinical Trial ID
NCT03898882
ParticipAid ID
bkRVKa
