Clinical Trial

CoMBAT Opioid Use Disorder

Study Description

CoMBAT Opioid Use Disorder

This study seeks primarily to test, in a two-arm randomized controlled trial (RCT), the feasibility, acceptability, and preliminary efficacy of CoMBAT OUD, an intervention that integrates Behavioral Activation (BA) and substance abuse and health navigation counseling for individuals who are receiving medications for opioid use disorder (i.e., methadone; suboxone) to help them improve engagement in care and opioid use treatment outcomes. Participants will be randomized 1:1 to two arms: (1) the CoMBAT intervention (2 sessions of substance abuse and health navigation counseling + 8 sessions of BA counseling); or the (3) the standard of care (SOC) comparison condition, including two equivalent substance abuse and health navigation counseling. Participants will be followed for 6 months post-randomization, with assessments at months 3 and 6.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - Substance Abuse and Health Navigation Counseling

2 standard substance abuse and health navigation counseling

Behavioral - Behavioral Activation (BA) Therapy

8 sessions of behavioral activation therapy

Medications for Opioid Use Disorder

Medications for opioid use disorder (i.e., buprenorphine and methadone) as prescribed by a community provider (not provided as part of the study).

Additional Information

Official Study Title

A Pilot RCT of a Combined Medication and Behavioral Activation Treatment for People Living With Opioid Use Disorder

Clinical Trial ID

NCT04240093

ParticipAid ID

bmZ1Ad