Clinical Trial

Drug Interaction Study

Study Description

Drug Interaction Study of the Effect on Cyclosporine on Ozanimod and Major Active Metabolites

This is a Phase 1, randomized, parallel-group, open-label study. Forty subjects will be enrolled and will be randomized into 1 of the 2 treatment groups, with 20 subjects in each treatment group(sex will be used as a stratifying factor) as follows: - Treatment Group A (reference): A single oral dose of ozanimod 0.46 mg - Treatment Group B (test): A single oral dose of ozanimod 0.46 mg plus a single oral dose of cyclosporine 600 mg

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Ozanimod

Ozanimod

Drug - Cyclosporine

Cyclosporine

Additional Information

Official Study Title

A Phase 1, Randomized, Parallel-group, Open-label Study to Evaluate the Effect of Cyclosporine on the Single-dose Pharmacokinetics of Ozanimod and Major Active Metabolites in Healthy Adult Subjects

Clinical Trial ID

NCT04149678

ParticipAid ID

bo2LKa