Clinical Trial

Berries, Inflammation, and Gut Microbiome

Study Description

Berries, Inflammation, and Gut Microbiome

The primary objectives are to characterize changes in indices of systemic and gut inflammation, assess host- and microbial-derived metabolite pools, and describe and link functional metagenomics and metatranscriptomic alterations in the gut microbiome with metabolite and inflammatory outcomes after acute (24hr) and chronic (4 week) intake of anthocyanins and ellagitannins from strawberry and red raspberries compared to a control diet (negative control), FOS (positive control, non-polyphenol, carbohydrate-based fermentable fiber/pre-biotic), or combination diet (berry composite + FOS) in human participants with low-grade inflammation.


Locations Selected Location


No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Dietary Supplement - Mixed berries

Strawberry and red raspberry

Dietary Supplement - FOS


Dietary Supplement - Control

Placebo similar in color to mixed berry supplement without any polyphenols

Dietary Supplement - Combination

Mixed berry composite + FOS

Additional Information

Official Study Title

Polyphenols and Human Gut Microbiome Interactions: Role of in Ameliorating Inflammation

Clinical Trial ID


ParticipAid ID