“Translational Model of Anhedonia”
The proposed research addresses a major mental health issue (anhedonia) with a novel computationally-inspired translational technique in both humans and mice. This approach greatly increases the likelihood that a positive animal model result will be successfully translated to humans. This research plan thus offers a novel way to address the NIMH's mission of defining mechanisms of complex behaviors.
Behavioral - Emotion Induction
Described in arm
A Novel Bench-to-Bedside Translational Model of Anhedonia