“Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion”
The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of human subjects and to determine whether this influences the oxalate passed in urine of healthy volunteers.
Low Oxalate Diet
Subjects will be instructed to ingest a controlled diet low in oxalate
Moderately high oxalate/low calcium diet
Subjects will be instructed to ingest a controlled diet moderately high in oxalate
Subjects will ingest liver preparation of O. formigenes
Oxalobacter Formigenes Colonization and Oxalate Excretion in Calcium Oxalate Kidney Stone Disease