Clinical Trial

Oxalobacter Formigenes Colonization in Healthy Subjects

Study Description

Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion

The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of human subjects and to determine whether this influences the oxalate passed in urine of healthy volunteers.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Low Oxalate Diet

Subjects will be instructed to ingest a controlled diet low in oxalate

Moderately high oxalate/low calcium diet

Subjects will be instructed to ingest a controlled diet moderately high in oxalate

Oxalobacter formigenes

Subjects will ingest liver preparation of O. formigenes

Additional Information

Official Study Title

Oxalobacter Formigenes Colonization and Oxalate Excretion in Calcium Oxalate Kidney Stone Disease

Clinical Trial ID

NCT03752684

ParticipAid ID

dwpnwe