Clinical Trial

High Altitude and Exogenous Carbohydrate Oxidation

Study Description

High Altitude and Exogenous Carbohydrate Oxidation

Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders. However, the mechanisms by which HA suppresses exogenous carbohydrate oxidation are not known. This study will seek to confirm that acute HA exposure decreases exogenous carbohydrate oxidation during steady-state aerobic exercise compared to SL, and explore if the mechanism inhibiting plasma glucose uptake is insulin dependent or independent.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Sea Level

Carbohydrate consumed at 1.8 g/min during treadmill exercise at SL

High Altitude

Carbohydrate consumed at 1.8 g/min during treadmill exercise at HA

Additional Information

Official Study Title

The Mechanistic Effects of Acute Hypobaric Hypoxia on Exogenous Carbohydrate Utilization During Steady-state Aerobic Exercise

Clinical Trial ID

NCT03851744

ParticipAid ID

dwpyge