“Effects of Overnight Low Oxygen Exposure on Energy Balance”
This research study will evaluate changes in resting metabolic rate, appetite, and heart rate variability following overnight exposure (8 h/night) to normobaric hypoxia (NH) or normobaric normoxic (NN). In randomized order, participants will sleep one night in NH conditions (~15% oxygen; achieved with nitrogen dilution, equivalent to ~8500 feet elevation) and another night in NN (control) conditions (~20% oxygen; achieved with nitrogen dilution, equivalent to ~1000 feet elevation).
Device - Normobaric Hypoxia
Low oxygen exposure to mimic ~8500 feet elevation.
Device - Normobaric Normoxia
Normal oxygen exposure to mimic ~1000 feet elevation (sham comparator).
Effects of an Overnight, 8-hour Low Oxygen Exposure on Resting Energy Expenditure and Appetite: a Pilot Study