Clinical Trial

Effects of Overnight Low Oxygen Exposure on Energy Balance

Study Description

Effects of Overnight Low Oxygen Exposure on Energy Balance

This research study will evaluate changes in resting metabolic rate, appetite, and heart rate variability following overnight exposure (8 h/night) to normobaric hypoxia (NH) or normobaric normoxic (NN). In randomized order, participants will sleep one night in NH conditions (~15% oxygen; achieved with nitrogen dilution, equivalent to ~8500 feet elevation) and another night in NN (control) conditions (~20% oxygen; achieved with nitrogen dilution, equivalent to ~1000 feet elevation).

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Device - Normobaric Hypoxia

Low oxygen exposure to mimic ~8500 feet elevation.

Device - Normobaric Normoxia

Normal oxygen exposure to mimic ~1000 feet elevation (sham comparator).

Additional Information

Official Study Title

Effects of an Overnight, 8-hour Low Oxygen Exposure on Resting Energy Expenditure and Appetite: a Pilot Study

Clinical Trial ID

NCT04151927

ParticipAid ID

dyPYWb