Clinical Trial

Neurocognitive Benefits of a Weight Management Program

Study Description

Neurocognitive Benefits of a Weight Management Program

This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images. In addition, it will evaluate whether weight loss can improve neural function when performing the N-back task, a measure of working memory. Findings will address notable gaps in the literature by testing whether a scalable weight loss intervention can help protect and improve neurocognitive functioning and brain health in individuals with obesity. This study will also provide important information about the effects of weight loss on neuroplasticity in brain regions crucial for memory and cognitive functioning, which will help to inform future interventions aimed at promoting brain health.


Locations Selected Location


No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - WW (formerly Weight Watchers)

The WW intervention will consist of weekly group workshops for 16 weeks with WW Coaches and Guides.

Behavioral - Waitlist

The waitlist group will have a 16-week waitlist period. After the waitlist period, they will be offered the WW intervention

Additional Information

Official Study Title

A Randomized Controlled Trial Examining the Neurocognitive Benefits of a Nationally Available Weight Management Program

Clinical Trial ID


ParticipAid ID