Clinical Trial

Ultralow Dose PAH Binary Mixture Study

Study Description

Ultralow Dose PAH Binary Mixture Study

Evaluation of the pharmacokinetics for [14C]-benzo[a]pyrene ([14C]-BaP) and metabolites in plasma and urine over 48 hours following a 50 ng dose (5.4 nCi) alone or with 1250 ng phenanthrene.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - [14C]-benzo[a]pyrene

Oral micro-dose (50 ng) (5.4 nCi)

Drug - [14C]-benzo[a]pyrene plus phenanthrene

Oral micro-dose of 50 ng (5.4 nCi) [14C]-benzo[a]pyrene plus 1250 ng phenanthrene

Additional Information

Official Study Title

Ultralow Dose PAH Binary Mixture Study

Clinical Trial ID

NCT03631667

ParticipAid ID

e1wrVb