Clinical Trial

VNS-Induced Corticospinal Plasticity

Study Description

VNS-induced Corticospinal Plasticity

The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.


Locations Selected Location


No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Paired-Associative Stimulation (PAS)

Simultaneous activation of connections in motor cortex via stimulation to the nerves and brain.

Vagus Nerve Stimulation (VNS)

Recruits the auricular branch of the vagus nerve which activates brain structures that release chemicals mediating cortical plasticity.

Sham Stimulation

Sub-threshold stimulation that does not activate neural structures.

Additional Information

Official Study Title

Mechanisms of Non-invasive Vagus Nerve Stimulation Underlying Enhanced Motor Control in Humans

Clinical Trial ID


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