“IPACK Study in Total Knee Arthroplasty Patients”
This study proposes to compare current multimodal analgesic treatment for TKA with a new multimodal analgesic regimen to demonstrate decreased opioid requirement, time to rehabilitation, and time to reach hospital discharge.
Drug - Standard of Care (ACB, SA, peri-op pain management)
INTERVENTION BEFORE SURGERY 1) Adductor Canal Block will be done using Adductor canal catheter (tube in the thigh) + injection of freezing medication INTERVENTION DURING SURGERY 1) IV propofol for sedation INTERVENTION AFTER SURGERY 1) injection of salty water through the tube in the thigh x 2
Drug - IPACK and multi-modal analgesic regimen
INTERVENTION BEFORE SURGERY Adductor Canal Block will be done using Adductor canal catheter (tube in the thigh) + injection of freezing medication iPACK block ( infiltration between Popliteal Artery and posterior Capsule of the Knee) - injection of freezing medication in the back of the knee INTERVENTION DURING SURGERY IV dexmedetomidine IV ketamine Both for sedation INTERVENTION AFTER SURGERY injection of freezing medication through the tube in the thigh x 2 IV dexamethasone 8 mg 1 day after su ...read more on ClinicalTrials.org
Opioid Sparing Analgesic Strategies for Enhanced Recovery After Total Knee Arthroplasty