Clinical Trial

IPACK Study in Total Knee Arthroplasty Patients

Study Description

IPACK Study in Total Knee Arthroplasty Patients

This study proposes to compare current multimodal analgesic treatment for TKA with a new multimodal analgesic regimen to demonstrate decreased opioid requirement, time to rehabilitation, and time to reach hospital discharge.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Standard of Care (ACB, SA, peri-op pain management)

INTERVENTION BEFORE SURGERY 1) Adductor Canal Block will be done using Adductor canal catheter (tube in the thigh) + injection of freezing medication INTERVENTION DURING SURGERY 1) IV propofol for sedation INTERVENTION AFTER SURGERY 1) injection of salty water through the tube in the thigh x 2

Drug - IPACK and multi-modal analgesic regimen

INTERVENTION BEFORE SURGERY Adductor Canal Block will be done using Adductor canal catheter (tube in the thigh) + injection of freezing medication iPACK block ( infiltration between Popliteal Artery and posterior Capsule of the Knee) - injection of freezing medication in the back of the knee INTERVENTION DURING SURGERY IV dexmedetomidine IV ketamine Both for sedation INTERVENTION AFTER SURGERY injection of freezing medication through the tube in the thigh x 2 IV dexamethasone 8 mg 1 day after su ...read more on ClinicalTrials.org

Additional Information

Official Study Title

Opioid Sparing Analgesic Strategies for Enhanced Recovery After Total Knee Arthroplasty

Clinical Trial ID

NCT03954379

ParticipAid ID

e9rPJa