Clinical Trial

Precision Nutrition and Metabolic Function

Study Description

Precision Nutrition and Metabolic Function

The purposes of this study are: 1) to determine the mechanisms responsible for the development of cardiometabolic complications in some, but not all people with obesity; 2) determine the best dietary approach for cardiometabolic health; and 3) understand why some people have a stable metabolic phenotype over time whereas cardiometabolic health improves or worsens in others.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Behavioral - Mediterranean diet

A Mediterranean-type diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.

Behavioral - Low-carbohydrate, ketogenic diet

A low-carbohydrate, ketogenic diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.

Behavioral - Low-fat diet

A low-fat diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.

Annual follow-up testing for 5 years

Annual follow-up testing with no restrictions on dietary intake during periods between annual testing.

Additional Information

Official Study Title

Precision Nutrition and Metabolic Function

Clinical Trial ID

NCT04131166

ParticipAid ID

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