Clinical Trial

Dosing Intervals of Opioid Medication for Chronic Pain

Study Description

Dosing Intervals of Opioid Medication for Chronic Pain

This study is to determine the feasibility of an n-of-1, randomized, double blind, placebo controlled case series to examine effects of extended release opioids when used at intervals shorter than recommended by the manufacturer by people with chronic pain.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Drug - Extended Release Opioid Formulation, Shortened Intervals

Extended release opioid, individualized total daily dose, dosing interval is less than every 12 hours

Drug - Extended Release Opioid Formulation, Standard intervals

Extended release opioid, individualized total daily dose, dosing interval is every 12 hours

Drug - Placebo oral tablet

Lactose pill manufactured to mimic extended release opioid formulation

Additional Information

Official Study Title

Examining the Relationship Amongst Opioid Subjective Effects and Pharmacokinetics of Extended Release Opioids at Shortened Dosing Intervals in Patients With Chronic Pain: a Randomized, Blinded, N-of-1 Case Series Feasibility Study

Clinical Trial ID

NCT04132011

ParticipAid ID

elYn6a