“Cardiac Sarcoidosis Randomized Trial”
Prospective randomized controlled trial comparing low dose Prednisone/Methotrexate combination to standard dose Prednisone in patients diagnosed with acute active clinically manifest cardiac sarcoidosis and not yet treated. The Investigators hypothesize that low dose Prednisone/Methotrexate combination will be as effective as standard dose Prednisone, and result in significantly better quality of life and less toxicity than standard dose Prednisone.
Drug - Prednisone
Oral prednisone tablet
Drug - Methotrexate
Oral, subcutaneous, or intramuscular methotrexate
Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial