Clinical Trial

Imaging of LAA Thrombosis

Study Description

Imaging of LAA Thrombosis

The purpose of the study is to evaluate a new radiotracer called 64Cu-FBP8 for PET-MR imaging of thrombosis. The tracer has the potential of detecting thrombosis in the left atrial appendage of patients with atrial fibrillation, thereby may provide a non-invasive alternative to the current standard-of-care, transesophageal echocardiography.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - [64Cu]FBP8

Injection of Copper-64 radiopeptide to detect thrombosis

Device - PET/MR

Whole body imaging using Siemens mMR PET/MR scanner

Procedure - Blood Collection

A total of 9 cc of blood sampled before, during, and after imaging for clinical chemistry

Procedure - Electrocardiogram

A standard 12-lead ECG will be obtained pre-and-post injection with radiotracer

Additional Information

Official Study Title

PET-MR Imaging of LAA Thrombosis

Clinical Trial ID

NCT03830320

ParticipAid ID

epYLra