Clinical Trial

Effects of Nicotine Salt Aerosol on Cigarette Smokers

Study Description

Effects of Nicotine Salt Aerosol on Cigarette Smokers

This grant compares the effects of cigarette smoking, protonated nicotine ("salt") aerosol, and unprotonated nicotine aerosol on nicotine delivery, nicotine craving, and other outcomes in cigarette smokers.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Subox Mini C with Avail 18 mg nicotine salt (protonated)

Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Subox Mini C with Avail 18 mg nicotine (unprotonated)

Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Own brand cigarette

Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.

Additional Information

Official Study Title

Effects of Nicotine Salt Aerosol on Cigarette Smokers

Clinical Trial ID

NCT03974152

ParticipAid ID

epYjQa