Clinical Trial

Topical Medications and Human Microbiome

Study Description

Alternation in the Human Microbiome With Commonly Used Topical Medications

The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Desonide 0.05%

Desonide 0.05% ointment topically twice daily for two weeks

Drug - Ketoconazole 2%

Ketoconazole 2% cream topically twice daily for two weeks

Additional Information

Official Study Title

Alterations in the Human Microbiome With Commonly Used Topical Medications

Clinical Trial ID

NCT03437005

ParticipAid ID

kazLOd